Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | wtNotch |
| GeneSet | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS |
| Enrichment Score (ES) | 0.8222277 |
| Normalized Enrichment Score (NES) | 1.6312475 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0416455 |
| FWER p-Value | 0.202 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SDHC | 3140347 6100156 | 4 | 5.878 | 0.1788 | Yes | ||
| 2 | PGK1 | 1570494 630300 | 8 | 5.004 | 0.3311 | Yes | ||
| 3 | PFKM | 1990156 5720168 | 21 | 4.511 | 0.4678 | Yes | ||
| 4 | PKM2 | 6520403 70500 | 34 | 3.793 | 0.5827 | Yes | ||
| 5 | TPI1 | 1500215 2100154 | 44 | 3.470 | 0.6879 | Yes | ||
| 6 | ENO3 | 5270136 | 302 | 1.532 | 0.7207 | Yes | ||
| 7 | ALDOA | 6290672 | 351 | 1.397 | 0.7607 | Yes | ||
| 8 | FBP1 | 1470762 | 594 | 1.016 | 0.7786 | Yes | ||
| 9 | PFKL | 6200167 | 918 | 0.751 | 0.7841 | Yes | ||
| 10 | ENO1 | 5340128 | 992 | 0.689 | 0.8011 | Yes | ||
| 11 | MDH2 | 1850601 | 1135 | 0.607 | 0.8120 | Yes | ||
| 12 | DLST | 2320722 | 1488 | 0.461 | 0.8071 | Yes | ||
| 13 | ACO1 | 50114 | 1791 | 0.366 | 0.8019 | Yes | ||
| 14 | SDHD | 2570128 | 1822 | 0.357 | 0.8112 | Yes | ||
| 15 | PGAM1 | 2570133 | 1830 | 0.354 | 0.8216 | Yes | ||
| 16 | ACO2 | 4230600 | 1995 | 0.311 | 0.8222 | Yes | ||
| 17 | CS | 5080600 | 2436 | 0.210 | 0.8049 | No | ||
| 18 | DLAT | 430452 | 2471 | 0.202 | 0.8093 | No | ||
| 19 | SDHB | 3120398 4780113 3710435 | 2612 | 0.178 | 0.8072 | No | ||
| 20 | DLD | 4150403 6590341 | 2678 | 0.169 | 0.8088 | No | ||
| 21 | PFKP | 70138 6760040 1170278 | 3109 | 0.120 | 0.7893 | No | ||
| 22 | IDH2 | 2680397 | 3502 | 0.085 | 0.7708 | No | ||
| 23 | PGAM2 | 3610605 | 3544 | 0.082 | 0.7711 | No | ||
| 24 | AMAC1 | 940270 | 3696 | 0.070 | 0.7651 | No | ||
| 25 | MDH1 | 6660358 6760731 | 5146 | 0.025 | 0.6879 | No | ||
| 26 | SUCLA2 | 730632 1170292 | 5976 | 0.016 | 0.6438 | No | ||
| 27 | PDHX | 870315 | 5988 | 0.016 | 0.6437 | No | ||
| 28 | FBP2 | 1580193 | 6917 | 0.010 | 0.5940 | No | ||
| 29 | PKLR | 1170400 2470114 | 9380 | 0.001 | 0.4615 | No | ||
| 30 | GAPDHS | 2690463 | 9513 | 0.001 | 0.4545 | No | ||
| 31 | SDHA | 7000056 | 10242 | -0.002 | 0.4153 | No | ||
| 32 | ALDOB | 4730324 | 11882 | -0.007 | 0.3273 | No | ||
| 33 | PGK2 | 2650091 | 13408 | -0.017 | 0.2458 | No | ||
| 34 | OGDH | 3840333 6350100 | 14904 | -0.050 | 0.1668 | No | ||
| 35 | ALDOC | 450121 610427 | 15231 | -0.069 | 0.1514 | No | ||
| 36 | BPGM | 5080520 | 15423 | -0.083 | 0.1436 | No | ||
| 37 | ENO2 | 2320068 | 16742 | -0.273 | 0.0810 | No | ||
| 38 | PDHB | 70215 610086 | 16745 | -0.273 | 0.0892 | No | ||
| 39 | IDH1 | 1990021 | 17109 | -0.377 | 0.0811 | No |
